Permissionless IV 2026

Join the Permissionless IV 2026, held from 24th to 26th June 2026, in Brooklyn, NY. It’s designed for technical founders, builders, developers, innovators, and buyers focused on shifting interest from middle infrastructure to real‑world packages in decentralized technology. The event capabilities include keynotes, panel discussions, workshops, networking opportunities, and a hackathon, covering topics like DeFi innovation, purchaser blockchain apps, protocol studies and layout, tokenomics, and the intersection of crypto with AI and Bitcoin development. It’s broadly regarded as a meeting wherein the destiny of on‑chain technology and decentralized finance is actively fashioned by using the community growing it.

Organized By

Blockworks is a key gathering for crypto founders, developers, and builders to collaborate and shape the future as the focus shifts from infrastructure to applications.

Event Highlights

• Focus shifts from infrastructure to applications
• Gathering for crypto technical founders, developers, and builders
• Opportunity to collaborate and shape the future of crypto

Event Themes

• DeFi Renaissance: RWAs, US capital formation, reshoring DeFi talent, and next-gen DeFi apps.
• Consumer Apps: Onchain apps, mobile, prediction markets, NFTs, gaming, loyalty, author financial system.
• Protocol R&D: Blockchain design, EVM/SVM/Move, rollups, scaling, modular vs monolithic, ZK, privacy.
• Token Design: Tokenomics, TGE, governance, application, price fashions, equity structures.
• Crypto x AI: Open-source AI, onchain verification, DePIN, AI agents, decentralized GPUs, incentivized training.
• Bitcoin: the supremacy of $BTC, network growth, scaling, and acceptance by institutions and nation-states.

Hackathon

• 36hr hackathon for solving complex problems
• Technical workshops for support
• Over $100,000 in prize bounties

Agenda

Day 1

• Welcome to Permissionless IV
• What Are We Building Towards?
• Making NYC the Crypto Capital of the World
• In Conversation with Peter Todd
• USPD: Permissionless Money
• The Next Bottleneck: Rethinking Real‑Time Infrastructure
• The Unintended Consequences of Digital Asset ETFs
• The Rise of AutoFi and System‑Level Automation

Day 2

• Sessions on DeFi’s Next Frontier and ecosystem trends
• Main Stage panels on Blockchain innovation and crypto market futures
• Discussions on Privacy & User‑First Web, Bitcoin Yield & BTCFi
• Panels on DeFi Renaissance, DEX/Multichain landscapes, and risk management
• Technical debates on Ethereum scaling, protocol design, and security
• Topics in Capital deployment, Venture state of the union, and Tokenization
• Crypto x AI-focused talks (future of AI + blockchain)

Day 3

• More Main Stage deep dives
• Strategic discussions on builder empowerment, open‑internet infrastructure, and decentralized identity
• Closing panels on industry outlook and innovation takeaways

Speakers

• Peter Todd - Founder, OpenTimestamps
• Brendan Eich - Co-Founder and CEO
• Kain Warwick - Founder
• Hayden Adams - Founder and CEO
• Joseph Lubin - Co-Founder of Ethereum

Permissionless IV 2026 brings together builders, innovators, and investors to drive the future of blockchain, DeFi, and crypto‑AI.